It is well known that the maximum fertility rate in women is at the age of 24 (fertility rate 86%), while the percentage in women 25-30 years old is about 78%. At age 30-34, fertility begins to decline (63%) and after the age of 35, it is more noticeable (52%). Natural conception is rare after the age of 45 (less than 0.1%).

Accurate estimation of ovarian reserve helps to predict responsiveness to stimulation and to properly predict the likelihood of pregnancy success in IVF cycles. The tests for the determination of ovarian reserve are FSH, E2, AMH and vaginal ultrasound.