Endometrial scars and atrophic, fine endometrium are usually the result of trauma and are associated with decreased blastocyst implantation.

The pathology of the isthmus and endocervical cavity can be linked to infertility. The obstruction creates a mechanical infertility factor, while scars, constrictions, encapsulated cysts (usually result of traumatic procedures) are associated with the production and consistency of cervical mucus.