We achieved an increase in pregnancy rates in poor responders with the administration of GnRH antagonists, according to our recent publication which is the world's largest study of its kind.

In our study, with the world's largest cohort of poor responders, the flexible GnRH antagonist protocol has proven to lead in a significant increase of ongoing pregnancy rates when compared with the short GnRH agonist protocol (Lainas et al., 2008).